Not biotransformation in the skin and cumulated in the stratum corneum. Found in the skin, even after 15 days from the time of its topical application. For external use fluocinolone acetonide may be slightly absorbed and cause a general phenomenon dragon pharma. After absorption is metabolized mostly in the liver. In the form winstrol only cycle of compounds with glucuronic acid and a small amount in the unbound form excreted through the kidneys and the bile slightly.
Indications Inflammatory diseases of the skin, measurable glucocorticosteroid therapy:
- atopic dermatitis;
- seborrheic dermatitis;
- psoriasis, including the scalp;
- erythema multiforme;
- lichen planus.
Contraindications: Hypersensitivity, cutaneous manifestations of syphilis, tuberculosis, skin, diaper rash, acne rosacea, extensive psoriatic lesions, anogenital pruritus, skin infections caused by bacteria, viruses, fungi; stanozolol winstrol only cycle wound skin damage, ulcers; erosive and ulcerative lesions of the gastrointestinal tract, tumors and precancerous skin condition; pregnancy, lactation, children’s age (up to 2 years). Precautions The girls at puberty.
Dosage and administration: Outwardly. At the pre-grated swab dipped in antiseptic liquid is applied to the skin a small amount of the drug 2-4 times a day and gently rubbed. The duration of treatment depends on the nature of the disease and usually is 5-10 days. If necessary, you can apply an occlusive dressing. Not allowed to be used by the band for more than 2 g / day. Shown in the first phase of treatment (before the ointment) and for the treatment of diseases of the scalp, as well as in the category of patients who can not tolerate the drug because of the ointment base. gel form allows to apply it in a small amount and, consequently, a smaller dose of drug on larger skin surface.
Side effects: Burning, itching, steroid acne, stretch marks, dry skin, folliculitis. With prolonged use – skin atrophy, local hirsutism, hypertrichosis, telangiectasia, purpura, pigmentation disorders of the skin, alopecia, especially in women, secondary immunodeficiency (exacerbation of chronic infectious diseases, the generalization of infection, opportunistic infections); when applied to large surfaces are possible systemic manifestations (gastritis, “steroid” stomach ulcers, adrenal insufficiency, Cushing’s syndrome, “steroid” diabetes, slowing of reparative processes).
Overdose Overdose with topical mesterolone only cycle observed very rarely. Symptoms include itching and burning of the skin at the site of application of the drug, hyperglycemia, glycosuria, Cushing’s syndrome. Treatment: symptomatic against the backdrop of a gradual withdrawal of the drug.
Interaction with other medicinal products is compatible with antimicrobial agents. Decreases antihypertensive activity, diuretic, anti-arrhythmic drugs, drugs K +. Diuretic drugs (except for potassium sparing) increase the risk of developing hypokalemia. During treatment should not glucocorticosteroids vaccination and immunization, in connection with the immunosuppressive effects of the drug.
Cautions When secondary infections at the site of the drug should use an antibacterial or antifungal treatment. With the utmost caution winstrol only cycle on the face, as the increased absorption of the drug and increases the possibility of side effects. To apply caution winstrol cycle in patients with existing atrophic skin changes, especially in the elderly. During treatment, it is recommended to mow loose clothing.
Effects on ability to drive the vehicle and the service moving parts. The product does not restrict the psychophysical activity, the ability to control the vehicle and the service moving mechanisms.